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Birth Injury

How Can AI and Next Generation Sequencing Help Children with Cerebral Palsy?

At the University of Delaware, researchers are using DNA and artificial intelligence to identify patients with spastic cerebral palsy (cp).

In a study recently published in BMC Bioinformatics, researchers at Nemours/Alfred I. duPont Hospital for Children and Genome Profiling LLC (GenPro) have been using advanced sequencing and artificial intelligence to detect variations in DNA methylation patterns, which suggest differences in the genomes of children with spastic CP. Researchers hope that by improving the process of detecting spastic CP, the result will be better treatment options for the condition.


“This blood test could be a game changer. The earlier the diagnosis, the earlier we can direct therapies at the child. Specifically, high intensity physical therapy and possibly early surgery to prevent more significant problems in the future, and hopefully improve overall function and quality of life.”

Dr. M. W. Shrader, Director of the Cerebral Palsy Centre at Nemours